CARELL GROUP – Publications


Publications in chronological order

2024 – Ludwig-Maximilians-Universität München (Germany)



A.J. Tölke, J.F. Gaisbauer, Y.V. Gärtner, B. Steigenberger, A. Holovan, F. Streshnev, S. Schneider, M. Müller, T. Carell

Angew. Chem. Int. Ed. 2024, 10.1002/anie.202405161

"Efficient Tandem Cu-Catalyzed Click Synthesis of Multi-Sugar-Modified Oligonucleotides"



E. WęgrzynI. MejdrováF. MüllerM. NainytėL. EscobarT. Carell

Angew. Chem. Int. Ed. 2024, 10.1002/anie.202319235

"RNA-Templated Peptide Bond Formation Promotes L-Homochirality"

2023 – Ludwig-Maximilians-Universität München (Germany)


P. Karousi, M. Samiotaki, M. Makridakis, J. Zoidakis, D. C. Sideris, A. Scorilas, T. Carell, C. K. Kontos

Funct. Integr. Genomics. 2023, 10.1007/s10142-023-01272-0

"3′-tRF-CysGCA overexpression in HEK-293 cells alters the global expression profile and modulates cellular processes and pathways."


A. Pichler, M. Hillmeier, M. Heiss, E. Peev, S. Xefteris, B. Steigenberger, I. Thoma, M. Müller, M. Borsò, A. Imhof, T. Carell

J.Am.Chem.Soc. 2023, 10.1021/jacs.3c10075

"Synthesis and Structure Elucidation of Glutamyl-Queuosine."


E.S. Schönegger, A. Crisp, M. Radukic, J. Burmester, T. Frischmuth, T. Carell

ChemBioChem 2023, 10.1002/cbic.202300701

"Orthogonal end labelling of oligonucleotides via dual incorporation of Click reactive NTP analogues."


F. Xu, S. Wiedemann, J. Feldmann, S. Becker, T. Carell

ChemistryEurope 2023, 10.1002/ceur.202300057

"An Aminoisoxazole-Based Proto-RNA."


M. Witzenberger, S. Burczyk , D. Settele, W. Mayer, L. M. Welp, M. Heiss, M. Wagner, T. Monecke, R. Janowski, T. Carell, H. Urlaub, S. M. Hauck, A. Voigt, D. Niessing

Nucleic Acids Res. 2023, 10.1093/nar/gkad565

"Human TRMT2A methylates tRNA and contributes to translation fidelity."


A. Nieborak, S. Lukauskas, J. Capellades, P. Heyn, G. S. Santos, K. Motzler, A. Zeigerer, R. Bester, U. Protzer, F. Schelter, M. Wagner, T. Carell, A. Hruscha, B. Schmid, O. Yanes, R. Schneider

Mol. Metab. 2023, 10.1016/j.molmet.2023.101748

"Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis"


J. Feldmann, M. K. Skaanning, M. Lommel, T. Kernmayr, P. Mayer, T. Carell

ChemistryEurope. 2023, 10.1002/ceur.202300013

"A Unifying Concept for the Prebiotic Formation of RNA Pyrimidine Nucleosides"


J. N. Singer, F. M. Müller, E. Węgrzyn, C. Hölzl, H. Hurmiz, C. Liu, L. Escobar, T. Carell

Angew. Chem. Intl. Ed. 2023, 10.1002/anie.202302360

"Loading of Amino Acids onto RNA in a Putative RNA-Peptide World"


N. Kuhl, A. Linder, N. Philipp, D. Nixdorf, H. Fischer, S. Veth, G. Kuut, T. T. Xu, S. Theurich, T. Carell, M. Subklewe, V. Hornung

EMBO Rep. 2023, 10.15252/embr.202255536

"STING agonism turns human T cells into interferon-producing cells but impedes their functionality"

2022 – Ludwig-Maximilians-Universität München (Germany)


B. Searle, M. Müller, T. Carell, A. Kellett

Angew. Chem. Intl. Ed. 2022, 10.1002/anie.202215704

"Third Generation Sequencing of Epigenetic DNA"


L. Montiel, F. Spada, A. Crisp, S. Serdjukow, T. Carell, T. Frischmuth

Chem. Eur. J. 2022, 10.1002/chem.202202633

"Divergent Synthesis of Ultrabright and Dendritic Xanthenes for Enhanced Click Chemistry-Based Bioimaging"


E.S. Schönegger, A. Crisp, M. Müller, J. Fertl, S. Serdjukow, S. Croce, M. Kollaschinski, T. Carell, T. Frischmuth

Bioconjugate Chem. 2022, 10.1021/acs.bioconjchem.2c00353

"Click Chemistry Enables Rapid Amplification of Full-Length Reverse Transcripts for Long-Read Third Generation Sequencing"


F. Xu, A. Crisp, T. Schinkel, R. C. A. Dubini, S. Hübner, S. Becker, F. Schelter, P. Rovó, T. Carell

Angew. Chem. Intl. Ed. 2022, 10.1002/anie.202211945

"Isoxazole Nucleosides as Building Blocks for a Plausible Proto-RNA."


M. Arroyo, F. D. Hastert, A. Zhadan, F. Schelter, S. Zimbelmann, C. Rausch, A. K. Ludwig, T. Carell, M. C.Cardoso

Nat. Commun. 2022, 10.1038/s41467-022-32799-8

"Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation."


B. I. Patel, M. Heiss, A. Samel-Pommerencke, T. Carell, A. E. Ehrenhofer-Murray

Biochem Biophys Res Commun. 2022, 10.1016/j.bbrc.2022.07.104

"Queuosine salvage in fission yeast by Qng1-mediated hydrolysis to queuine."


S. Stazzoni, D. F. R. Böhmer, F. Hernichel, D. Özdemir, A. Pappa, D. Drexler, S. Bauernfried, G. Witte, M. Wagner, S. Veth, K.-P. Hopfner, V. Hornung, L. M. König, T. Carell

Angew. Chem. Int. Ed. 2022, 10.1002/anie.202207175

"Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists."


F. R. Traube, M. Stern, A. J. Tölke, M. Rudelius, E. Mejías-Pérez, N. Raddaoui, B. M. Kümmerer, C. Douat, F. Streshnev, M. Albanese, P. R. Wratil, Y. V. Gärtner, M. Nainytė, G. Giorgio, S. Michalakis, S. Schneider, H. Streeck, M. Müller, O. T. Keppler, T. Carell

Angew. Chem. Int. Ed. 2022, 10.1002/anie.202204556

"Suppression of SARS-CoV-2 Replication with Stabilized and Click-Chemistry modified siRNAs."


M. Czuppa, A. Dhingra, Q. Zhou, C. Schludi, L. König, E. Scharf, D. Farny, A. Dalmia, J. Täger, M. Castillo-Lizardo, E. Katona, K. Mori, T. Aumer, F. Schelter, M. Müller, T. Carell, T. Kalliokoski, J. Messinger, P. Rizzu, P. Heutink, D. Edbauer

Cell Rep. 2022, 10.1016/j.celrep.2022.110913

"Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD."


R. C. A. Dubini, E. Korytiaková, T. Schinkel, P. Heinrichs, T. Carell, P. Rovó

ACS Phys. Chem Au 2022, 10.1021/acsphyschemau.1c00050

"1H NMR Chemical Exchange Techniques Reveal Local and Global Effects of Oxidized Cytosine Derivatives."


F. Müller, L. Escobar, F. Xu, E. Węgrzyn, M. Nainytė, T. Amatov, C.-Y. Chan, A. Pichler, T. Carell

Nature 2022, 10.1038/s41586-022-04676-3

"A prebiotically plausible scenario of an RNA–peptide world."


F. R. Traube, N. F. Brás, W. P. Roos, C. C. Sommermann, T. Diehl, R. J. Mayer, A. R. Ofial, M. Müller, H. Zipse, T. Carell

Chemistry 2022, 10.1002/chem.202200640

"Epigenetic anti-cancer treatment with a stabilized carbocyclic Decitabine analogue."


S. Veth, A. Fuchs, D. Özdemir, C. Dialer, D. J. Drexler, F. Knechtel, G. Witte, K.-P. Hopfner, T. Carell, E. Ploetz

Chembiochem2022, 10.1002/cbic.202200005

"Chemical synthesis of the fluorescent, cyclic dinucleotides cthGAMP."


H. Panosyan, F. R. Traube, C. Brandmayr, M. Wagner, T. Carell

Extremophiles 2022, 10.1007/s00792-022-01258-z

"tRNA modification profiles in obligate and moderate thermophilic bacilli."


M.A. Margreiter, M. Witzenberger, Y. Wasser, E. Davydova, R. Janowski, J. Metz, P. Habib, S.E.M. Sahnoun, C. Sobisch, B. Poma, O. Palomino-Hernandez, M. Wagner, T. Carell, N. Jon Shah, J.B. Schulz, D. Niessing, A. Voigt, G. Rossetti

Comput. Struct. Biotechnol. J. 2022, 10.1016/j.csbj.2021.12.029

"Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death."

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