Thomas Carell – Carell GroupThomas Carell – Carell Group

CARELL GROUP – Publications

 

Publications in chronological order

2020 – Ludwig-Maximilians-Universität München (Germany)

 

260

C. B. Mulholland, A. Nishiyama, J. Ryan, R. Nakamura, M. Yiğit, I. M. Glück, C. Trummer, W. Qin, M. D. Bartoschek, F. R. Traube, E. Parsa, E. Ugur, M. Modic, A. Acharya, P. Stolz, C. Ziegenhain, M. Wierer, W. Enard, T. Carell, D. C. Lamb, H. Takeda, M. Nakanashi, S. Bultmann, H. Leonhardt

Nat. Commun. 2020, 10.1038/s41467-020-19603-1

“Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals.” 

 

 

 

 

Link to publication

 

 

 

259

J. B. Alberge, F. Magrangeas, M. Wagner, S. Denié, C. Guérin-Charbonnel, L. Campion, M. Attal, H. Avet-Loiseau, T. Carell, P. Moreau, S. Minvielle, A. A. Sérandour.

Clin. Epigenetics 2020, 10.1186/s13148-020-00953-y

“DNA hydroxymethylation is associated with disease severity and persists at enhancers of oncogenic regions in multiple myeloma” 

 

 

 

Link to publication

 

 

258

F. Spada, S. Schiffers, A. Kirchner, Y.-Q. Zhang, G. Arista, O. Kosmatchev, E. Korytiakova, R. Rahimoff, C. Ebert, T. Carell

Nat. Chem. Biol. 2020, 10.1038/s41589-020-0621-y

“Active turnover of genomic methylcytosine in pluripotent cells” 

 

Link to publication

 

257

T. Lauria, C. Slator, V. McKee, M. Müller, S. Stazzoni, A. L. Crisp, T. Carell, A. Kellett

Chemistry. 2020, 10.1002/chem.202002860

“A Click Chemistry Approach to Developing Molecularly Targeted DNA Scissors” 

 

 

Link to publication

 

256

C. B. Mulholland, F. R. Traube, E. Ugur, E. Parsa , E. M. Eckl, M. Schönung, M. Modic, M. D. Bartoschek, P. Stolz, J. Ryan, T. Carell, H. Leonhardt, S. Bultmann

Sci. Rep. 2020, 10.1038/s41598-020-68600-3

“Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency.” 

 

Link to publication

255

R. C. A. Dubini, A. Schön , M. Müller, T. Carell, P. Rovó

Nucleic Acids Res. 2020, 10.1093/nar/gkaa589

“Impact of 5-formylcytosine on the melting kinetics of DNA by 1H NMR chemical exchange” 

 

Link to publication

254

M. Nainytè, F. Müller, G. Ganazzoli, C.-Y. Chan, A. Crisp, D. Globisch, T. Carell

Chem. Eur. J. 2020, 10.1002/chem202002929

“Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA-Peptide World”

 

 

Link to publication

253

N. Raddaoui, S. Croce, F. Geiger, A. Borodavka, L. Möckl, S. Stazzoni, B. Viverge, C. Bräuchle, T. Frischmuth, H. Engelke, T. Carell

ChemBioChem 2020, doi: 10.1002/cbic.202000081

“Super-sensitive multi-fluorophore RNA-FISH for early virus detection and flow-FISH using click chemistry”

 

Link to publication

252

E. C. Beckwitt, S. Jang, I. C. Detweiler, J. Kuper, F. Sauer, N. Simon, J. Bretzler, S. C. Watkins, T. Carell, C. Kisker, B. Van Houten

Nat. Comm. 2020, doi: 10.1038/s41467-020-15168-1

“Single molecule analysis reveals monomeric XPA bends DNA and undergoes episodic linear diffusion during damage search”

 

Link to publication

251

P. Thumbs, T. T. Ensfelder, M. Hillmeier, M. Wagner, M. Heiss, C. Scheel, A. Schön, M. Müller, S. Michalakis, S. Kellner, T. Carell

Angew. Chem. Int. Ed. 2020, doi: 10.1002/anie.202002295

“Synthesis of galactosyl‐queuosine and distribution of hypermodified Q‐nucleosides in mouse tissues”

 

Link to publication

250

M. Nainyté, T. Carell

Helv. Chim. Acta 2020, doi: 10.1002/hlca.202000016

"Synthesis and incorporation of k2U into RNA"

 

Link to publication

249

A. Schön, E. Kaminska, F. Schelter, E. Ponkkonen, E. Korytiaková, S. Schiffers, T. Carell

Angew. Chem. Int. Ed. 2020, doi: 10.1002/anie.202000414

"Analysis of an active deformylation mechanism of 5-formyl-deoxycytidine (fdC) in stem cells"

 

Link to publication

248

S. Croce, S. Serdjukow, T. Carell, T. Frischmuth

ChemBioChem 2020, doi: 10.1002/cbic.201900718

"Chemo‐Enzymatic Preparation of Functional Click Labelled Messenger RNA"

 

Link to publication

2019 – Ludwig-Maximilians-Universität München (Germany)

247

W. Greulich, M. Wagner, M.M. Gaidt, C. Stafford, Y. Cheng, A. Linder, T. Carell, V. Hornung

Cell 2019, doi: 10.1016/j.cell.2019.11.001

"TLR8 Is a Sensor of RNase T2 Degradation Products"

 

Link to publication

In the press

A. Crisp

Nature - Behind the Paper 2019

"Purines and Pyrimidines: Structure out of Soup"

 

Link to publication

246

M. Stadlmeier, L. S. Runtsch, F. Streshnev, M. Wühr, T. Carell

ChemBioChem. 2019, doi: 10.1002/cbic.201900611

"A Click‐chemistry based enrichable cross‐linker for structural and protein interaction analysis by mass spectrometry"

 

Link to publication

245

S. Becker, J. Feldmann, S. Wiedemann, H. Okamura, C. Schneider, K. Iwan, A. Crisp, M. Rossa, T. Amatov, T. Carell

Science 2019, doi: 10.1126/science.aax2747

"Unified prebiotically plausible synthesis of pyrimidine and purine RNA ribonucleotides"

 

Link to publication

244

H. Okamura, A. Crisp, S. Hübner, S. Becker, P. Rovo, T. Carell

Angew. Chem. Int. Ed. 2019, doi: 10.1002/anie.201911746

"proto‐Urea‐RNA (Wöhler RNA) containing unusually stable urea nucleosides"

 

Link to publication

243

S. A. Benner, E. A. Bell, E. Biondi, R. Brasser, T. Carell, H.-J. Kim, S. J. Mojzsis, A. Omran, M. A. Pasek, D. Trail

ChemSystemsChem 2019, doi: 10.1002/syst.201900035

"When Did Life Likely Emerge on Earth in an RNA‐First Process?"

 

Link to publication

242

J. Gontcharov, B. Pilles, L. Liu, T. Carell, W. Schreier, W. Zinth

Chem. E. J. 2019, doi: 10.1002/chem.201903573

"Triplet Induced Lesion Formation at CpT and TpC sites in DNA"

 

Link to publication

241

M. Nainytė, T. Amatov, T. Carell

Chem. Commun. 2019, doi: 10.1039/c9cc06314e

"Synthesis of an acp3U phosphoramidite and incorporation of the hypermodified base into RNA"

 

Link to publication

240

N. Kitsera, M. Rodriguez-Alvarez, S. Emmert, T. Carell, A. Khobta

Nucleic Acids Res. 2019, doi: 10.1093/nar/gkz558

"Nucleotide excision repair of abasic DNA lesions"

 

Link to publication

239

T. M. Wildenhof, S. Schiffers, F. R. Traube, P. Mayer, T. Carell

Angew. Chem. Int. Ed. 2019, doi: 10.1002/anie.201904794

"Influencing epigenetic information with a hydrolytically stable carbocyclic 5-aza-2'-deoxycytidine"

 

Link to publication

238

S. Schiffers, T. M. Wildenhof, K. Iwan, M. Stadlmeier, M. Müller and T. Carell

Helv. Chim. Acta. 2019, doi: 10.1002/hlca.201800229

"Label‐Free Quantification of 5‐Azacytidines Directly in the Genome"

 

Link to publication

237

H. Okamura, S. Becker, N. Tiede, S. Wiedemann, J. Feldmann and T. Carell

Chem. Commun. 2019, doi: 10.1039/C8CC09435G

"A one‐pot, water compatible synthesis of pyrimidine nucleobases under plausible prebiotic conditions"

 

>>highlighted in Synfacts 2019; 15(05): 0476, DOI: 10.1055/s-0037-1612513

 

Link to publication

2018 – Ludwig-Maximilians-Universität München (Germany)

236

F.R. Traube, S. Schiffers, K. Iwan, S. Kellner, F. Spada, M. Müller, T. Carell

Nat. Protoc. 2018, doi: 10.1038/s41596-018-0094-6

"Isotope-dilution mass spectrometry for exact quantification of noncanonical DNA nucleosides"

 

Link to publication

235

S. Becker, C. Schneider, A. Crisp, T. Carell

Nat. Commun. 2018, doi: 10.1038/s41467-018-07222-w

"Non-canonical nucleosides and chemistry of the emergence of life"

 

Link to publication

234

C. R. Dialer, S. Stazzoni, D. J. Drexler, F. M. Müller, S. Veth, A. Pichler, H. Okamura, G. Witte, K.-P. Hopfner and T. Carell

Chem. Eur. J. 2018, doi: 10.1002/chem.201805409

"A Click-Chemistry Linked 2'3'-cGAMP Analog"

 

>> highlighted in Synfacts 2019; 15(04): 0434; DOI: 10.1055/s-0037-1612408

 

Link to publication

In the press

Robert F. Service

Science News 2018, doi: 10.1126/science.aav7778

"Chemists find a recipe that may have jump-started life on Earth"

 

Link to publication

233

A. Rajavelu, C. Lungu, M. Emperle, M. Dukatz, A. Brohm, J. Broche, I. Hanelt, E. Parsa, S. Schiffers, R. Karnik, A. Meissner, T. Carell, P. Rathert, R. Z. Jurkowska, A. Jeltsch

Nucleic Acids Res. 2018, doi: 10.1093/nar/gky715

"Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2"

 

Link to publication

232

T. T. Ensfelder, M. Q. Kurz, K. Iwan, S. Geiger, S. Matheisl, M. Müller, R. Beckmann, T. Carell

Chem. Commun. 2018, doi: 10.1039/C8CC03980A

"ALKBH5-Induced Demethylation of Mono- and Dimethylated Adenosine"

 

Link to publication

231

A. Crisp, T. Carell

eLife 2018, doi: 10.7554/eLife.38297

"In Vitro Evolution: Rethinking the tools of the RNA world"

 

Link to publication

230

C. Schneider, S. Becker, H. Okamura, A. Crisp, T. Amatov, M. Stadlmeier, T. Carell

Angew. Chem. Int. Ed. 2018, doi:10.1002/anie.201801919

"Noncanonical RNA Nucleosides as Molecular Fossils of an Early Earth—Generation by Prebiotic Methylations and Carbamoylations"

 

Link to publication

229

S. Becker, C. Schneider, H. Okamura, A. Crisp, T. Amatov, M. Dejmek, T. Carell

Nat. Commun. 2018, doi:10.1038/s41467-017-02639-1

"Wet-dry cycles enable the parallel origin of canonical and non-canonical nucleosides by continuous synthesis"

 

Link to publication

228

M. Stadlmeier, J. Bogena, M. Wallner, T. Carell

Angew. Chem. Int. Ed. 2018, doi:10.1002/anie.201708867

"A sulfoxide-based isobaric labelling reagent for accurate quantitative mass spectrometry"

 

Link to publication

2017 – Ludwig-Maximilians-Universität München (Germany)

227

K. Iwan, R. Rahimoff, A. Kirchner, F. Spada, A.S. Schröder, O. Kosmatchev, S. Ferizaj, J. Steinbacher, E. Parsa, M. Müller, T. Carell

Nat. Chem. Biol. 2017, doi:10.1038/nchembio.2531

"5-Formylcytosine to cytosine conversion by C-C bond cleavage in vivo"

 

Link to publication

226

I.N. Michaelides, N. Tago, B. Viverge, T. Carell

Chem. Eur. J. 2017, doi: 10.1002/chem.201704216

"Synthesis of RNA Containing 5-Hydroxymethyl-, 5-Formyl-, and 5-Carboxycytidine"

 

Link to publication

225

T. Carell, M.Q. Kurz, M. Müller, M. Rossa, F. Spada

Angew. Chem. Int. Ed. 2017, doi: 10.1002/anie.201708228

"Non-canonical bases in the genome: The regulatory information layer in DNA"

 

 

Link to publication

 

224

R.R. Edupuganti, S. Geiger, R.G.H. Lindeboom, H. Shi, P.J. Hsu, Z. Lu, S.-Y. Wang, M.P.A. Baltissen, P.W.T.C. Jansen, M. Rossa, M. Müller, H.G. Stunnenberg, C. He*, T. Carell*, M. Vermeulen*

Nat. Struct. Mol. Biol. 2017, doi:10.1038/nsmb.3462

"N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis"

 

Link to publication

223

N. Kitsera, J. Allgayer, E. Parsa, N. Geier, M. Rossa, T. Carell, A. Khobta

Nucleic Acids Res. 2017, doi: 10.1093/nar/gkx718

"Functional impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter."

 

Link to publication

222

R. Rahimoff, O. Kosmatchev, A. Kirchner, T. Pfaffeneder, F. Spada, V. Brantl, M. Müller, T. Carell

J. Am. Chem. Soc. 2017, doi: 10.1021/jacs.7b04131

"5-Formyl- and 5-carboxydeoxycytidines do not cause accumulation of harmful repair intermediates in stem cells."

 

Link to publication

221

N. Raddaoui, S. Stazzoni, L. Möckl, B. Viverge, F. Geiger, H. Engelke, C. Bräuchle, T. Carell

ChemBioChem 2017, doi: 10.1002/cbic.201700209

"Dendrimer-based signal amplification of click-labelled DNA in situ."

 

Link to publication

220

F. R. Traube, T. Carell

RNA Biol. 2017, 25, 1-9 doi: 10.1080/15476286

"The chemistries and consequences of DNA and RNA methylation and demethylation."

 

Link to publication

219

C. Ebert, N. Simon, S. Schneider, T. Carell

ChemBioChem 2017, doi: 10.1002/cbic.201700169

"Structural insights into the recognition of N2-aryl- and C8-aryl DNA lesions by the repair protein XPA/Rad14."

 

Link to publication

218

S. Schiffers, C. Ebert, R. Rahimoff, O. Kosmatchev, J. Steinbacher, A.-V. Bohne, F. Spada, S. Michalakis, M. Müller, T. Carell

Angew. Chem. Int. Ed. 2017, doi: 10.1002/anie.201700424

"Quantitative LC-MS Provides No Evidence for m6dA or m4dC in the Genome of Mouse Embryonic Stem Cells and Tissues."

 

Link to publication

2016 – Ludwig-Maximilians-Universität München (Germany)

217

A. S. Schröder, E. Parsa, K. Iwan, F. R. Traube, M. Wallner, S. Serdjukow, T. Carell

Chem. Commun. 2016, doi:10.1039/C6CC07517G

"2´-(R)-Fluorinated mC, hmC, fC and caC triphosphates are substrates for DNA polymerases and TET-enzymes."

 

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216

L. Heidinger, A. Kneuttinger, G. Kazshiwazaki, S. Weber, T. Carell, E. Schleicher

FEBS Lett. 2016, doi:10.1002/1873-3468.12498

"Direct Observation of a Deoxyadenosyl Radical in an Active Enzyme Environment."

 

Link to publication

215

A. Dallmann, A. Beribisky, F. Gnerlich, M. Rübbelke, S. Schiesser, T. Carell, M. Sattler

Chem. Eur. J. 2016, 22(43), 15350-15359 doi:10.1002/chem.201602784

"Site-Specific Isotope-Labeling of Inosine Phosphoramidites and NMR Analysis of an Inosine-Containing RNA Duplex."

 

Link to publication

214

M. Su, A. Kirchner, S. Stazzoni, M. Müller, M. Wagner, A. S. Schröder, T. Carell

Angew. Chem. Int. Ed. 2016, 55(39), 11797-11800 doi:10.1002/anie.201605994

"5-Formylcytosine could be a Semipermanent Base in Specific Genome Sites."

 

Link to publication

213

A. S. Schröder, O. Kotljarova, E. Parsa, K. Iwan, N. Raddaoui, T. Carell

Org. Lett. 2016, 18(17), 4368-4371 doi:10.1021/acs.orglett.6b02110

"Synthesis of (R)-Configured 2´-Fluorinated mC, hmC, fC, and caC Phosphoramidites and Oligonucleotides."

 

Link to publication

212

B. Thienpont, J. Steinbacher, H. Zhao, F. D'Anna, A. Kuchnio, A. Ploumakis, B. Ghesquière, L. Van Dyck, B. Boeckx, L. Schoonjans, E. Hermans, F. Amant, V. N. Kristensen, K. P. Koh, M. Mazzone, M. L. Coleman, T. Carell, P. Carmeliet, D. Lambrechts

Nature, 2016, 537, 63-68 doi:10.1038/nature19081

"Tumour hypoxia causes DNA hypermethylation by reducing TET activity."

 

Link to publication

211

C. M. Greco, P. Kunderfranco, M. Rubino, V. Larcher, P. Carullo, A. Anselmo, K. Kurz, T. Carell, A. Angius, M. V. G. Latronico, R. Papait, G. Condorelli

Nature Comm. 2016, 7, 12418 doi:10.1038/ncomms12418

"DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy."

 

Link to publication

210

N. Simon, C. Ebert, S. Schneider

Chem. Eur. J. 2016, 22(31), 10782-10785 doi:10.1002/chem.201602438

"Structural Basis for Bulky-Adduct DNA-Lesion Recognition by the Nucleotide Excision Repair Protein Rad14."

 

Link to publication

209

S. Becker, I. Thoma, A. Deutsch, T. Gehrke, P. Mayer, H. Zipse, T. Carell

Science, 2016, 352(6287), 833-836 doi:10.1126/science.aad2808

"A high-yielding, strictly regioselective prebiotic purine nucleoside formation pathway."

 

Link to publication

208

S. C. Koch, N. Simon, C. Ebert, T. Carell

Quaterly Reviews of Biophysics, 2016, 49, e5 doi:10.1017/S0033583515000268

"Molecular mechanisms of xeroderma pigmentosum (XP) proteins."

 

Link to publication

207

O. Bogdanovic, A. H. Smits, E. de la Calle Mustienes, J. J. Tena, E. Ford, R. Williams, U. Senanayake, M. D. Schultz, S. Hontelez, I. van Kruijsbergen, T. Rayon, F. Gnerlich, T. Carell, G. J. C. Veenstra, M. Manzanares, T. Sauka-Spengler, J. R. Ecker, M. Vermeulen, J. L. Gómez-Skarmeta, R. Lister

Nature Genetics, 2016, 48, 417-426 doi:10.1038/ng.3522

"Active DNA demethylation at enhancers during the vertebrate phylotypic period."

 

Link to publication

206

L. Klier, E. Aranzamendi, D. Ziegler, J. Nickel, K. Karaghiosoff, T. Carell, P. Knochel

Org. Lett. 2016, 18(5), 1068-1071 doi:10.1021/acs.orglett.6b00190

"Lewis Acid Triggered Regioselective Magnesiation and Zincation of Uracils, Uridines, and Cytidines."

 

Link to publication

205

S. Datz, C. Argyo, M. J. Gattner, V. Weiss, K. Brunner, J. Bretzler, C. von Schirnding, A. A. Torrano, F. Spada, M. Varbel, H. Engelke, C. Bräuchle, T. Carell, T. Bein

Nanoscale, 2016, 8, 8101-8110 doi:10.1039/C5NR08163G

"Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release."

 

Link to publication

204

D. B. Bucher, C. L. Kufner, A. S. Schulter, T. Carell, W. Zinth

J. Am. Chem. Soc. 2016, 138(1), 186-190 doi:10.1021/jacs.5b09753

"UV-Induced Charge Transfer States in DNA Promote Sequence Selective Self-Repair."

 

Link to publication

2015 – Ludwig-Maximilians-Universität München (Germany)

203

N. C. Gassen, G. R. Fries , A. S. Zannas , J. Hartmann , J. Zschocke , K. Hafner , T. Carrillo-Roa , J. Steinbacher , S. N. Preißinger , L. Hoeijmakers , M. Knop , F. Weber , S. Kloiber , S. Lucae , G.P. Chrousos , T. Carell , M. Ising , E. B. Binder , M. V. Schmidt , J. Rüegg , T. Rein

Science Signal. 2015, 8(404), ra119, doi:10.1126/scisignal.aac7695

"Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine."

 

Link to publication

202

D. B. Bucher, B. M. Pilles, T. Carell, W. Zinth

J. Phys. Chem. B, 2015, 119(28), 8685-8692

"Dewar Lesion Formation in Single- and Double-Stranded DNA is Quenched by Neighboring Bases."

 

Link to publication

201

M. Wagner, J. Steinbacher, T. F. Kraus, S. Michalakis, B. Hackner, T. Pfaffeneder, A. Perera, M. Müller, A. Giese, H. A. Kretzschmar, T. Carell

Angew. Chem. Int. Ed. 2015, 54(42), 12511-12514 doi:10.1002/anie.2015027225

"Age-Dependent Levels of 5-Methyl-, 5-Hydroxymethyl-, and 5-Formylcytosine in Human and Mouse Brain Tissues."

 

Link to publication

200

L. Schuster, L. Rothmund, X. He, Kirsten L. V. Landuyt, H. Schweikl, E. Hellwig, T. Carell, R. Hickel, F.-X. Reichl, C. Högg

Dent. Mater. 2015, 31(6), 745-757

"Effect of Opalescence® bleaching gels on the elution of dental composite components."

 

Link to publication

199

S. C. Koch, J. Kuper, K. L. Gasteiger, N. Simon, R. Strasser, D. Eisen, S. Geiger, S. Schneider, C. Kisker, T. Carell

PNAS, 2015, doi:10.1073/pnas.1508509112

"Structural insights into the recognition of cisplatin and AAF-dG lesion by Rad14 (XPA)"

 

Link to publication

198

L. Rothmund, M. Shehata, K. L. Van Landuyt, H. Schweikl, T. Carell, W. Geurtsen, E. Hellwig, R. Hickel, F.-X. Reichl, C. Högg

Dent. Mater. 2015, 31(6), 496-504 doi:10.1016/j.dental.2015.01.016

"Release and protein binding of components from resin based composites in native saliva and other extraction media"

 

Link to publication

197

S. Schiesser, B. Hackner, M. Vrabel, W. Beck, T. Carell

Eur. J. Org. Chem. 2015, 2654-2660

"Synthesis and DNA-Damaging Properties of Cisplatin-N-Mustard Conjugates"

 

Link to publication

196

M Ehrlich, M. J. Gattner, B. Viverge, J. Bretzler, D. Eisen, M. Stadlmeier, M. Vrabel, T. Carell

Chem. Eur. J. 2015, 21, 1-5

"Orchestrating the Biosynthesis of an Unnatural Pyrrolysine Amino Acid for Its Direct Incorporation into Proteins Inside Living Cells"

 

Link to publication

195

A. Perera, D. Eisen, M. Wagner, S. K. Laube, A. F. Künzel, S. Koch, J. Steinbacher, E. Schulze, V. Splith, N. Mittermeier, M. Müller, M. Biel, T. Carell, S. Michalakis

Cell Rep. 2015, 11, 1-12

"TET3 Is Recruited by REST for Context-Specific Hydroxymethylation and Induction of Gene Expression"

 

Link to publication

194

L. Penter, B. Maier, U. Frede, B. Hackner, T. Carell, C. Hagemeier, M. Truss

Target Oncol. 2015, doi:10.1007/s11523-014-0354-5

"A rapid screening system evaluates novel inhibitors of DNA methylation and suggests F-box proteins as potential therapeutic targets for high-risk neuroblastoma"

 

Link to publication

193

M. Su, M. Tomas–Gamasa, T. Carell

Chem. Sci. 2015, 6, 632-638

"DNA based multi-copper ions assembly using combined pyrazole and salen ligandosides"

 

Link to publication

2014 – Ludwig-Maximilians-Universität München (Germany)

192

K. Brunner, J. Harder, T. Halbach, J. Willibald, F. Spada, F. Gnerlich, K. Sparrer, A. Beil, L. Möckl, C. Bräuchle, K-K Conzelmann, T. Carell

Angew. Chem. Int. Ed. 2014, 53, 1-5

"Cell-Penetrating and Neurotargeting Dendritic siRNA Nanostructures"

 

Link to publication

191

M. Tomas–Gamasa, S. Serdjukow, M. Su, M. Müller, T. Carell

Angew. Chem. Int. Ed. 2014, 54, 796-800

"Post-It" Type Connected DNA Created with a Reversible Covalent Cross-Link

 

Link to publication

190

O. Ziv, A. Zeisel, N. Mirlas-Neisberg, U. Swain, R. Nevo, N. Ben-Chetrit, M. Paola Martelli, R. Rossi, S.n Schiesser, C. E. Canman, T. Carell, N. E. Geacintov, B. Falini, E. Domany, Z. Livneh

Nature Comm. 2014, 5:5437

"Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin."

 

Link to publication

189

A. Benjdia, K. Heil, A. Winkler, T. Carell, I. Schlichting.

Chem. Commun. 2014, 50, 14201-14204

"Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase"

 

Link to publication

188

D. B. Bucher, A. Schlueter, T. Carell, W. Zinth

Angew. Chem. Int. Ed. 2014, 53, 11366-11369

"Watson-Crick Base Pairing Controls Excited-State Decay in Natural DNA"

 

Link to publication

187

A. Biela, F. Coste, F. Culard, M. Guerin, S. Goffinont, K. Gasteiger, J. Cieśla, A. Winczura, Z. Kazimierczuk, D. Gasparutto, T. Carell, B. Tudek, B. Castaing

Nucleic Acids Res. 2014, 42, 10748-10761

"Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization"

 

Link to publication

186

K. Sadeghian, D. Flaig, I. D. Blank, S. Schneider, R. Strasser, D. Stathis, M. Winnacker, T. Carell, C. Ochsenfeld

Angew. Chem. Int. Ed. 2014, 53, 10044-10048

"Ribose-Protonated DNA Base Excision Repair: A Combined Theoretical and Experimental Study"

 

Link to publication

185

L. I. Kroeze, M. G. Aslanyan, A. van Rooij, T. N. Koorenhof-Scheele, M. Massop, T. Carell, J. B. Boezeman, J.-P. Marie, C. J. M. Halkes, T. de Witte, G. Huls, S. Suciu, R. A. Wevers, B. A. van der Reijden, J. H. Jansen

Blood 2014, 124, 1110-1118

"Characterization of acute myeloid leukemia based on levels of global hydroxymethylation"

 

Link to publication

184

T. Pfaffeneder, F. Spada, M. Wagner, C. Brandmayr, S. K. Laube, D. Eisen, M. Truss, J. Steinbacher, B. Hackner, O. Kotljarova, D. Schuermann, S. Michalakis, O. Kosmatchev, S. Schiesser, B. Steigenberger, N. Raddaoui, G. Kashiwazaki, U. Müller, C. G. Spruijt, M. Vermeulen, H. Leonhardt, P. Schär, M. Müller & T. Carell

Nature Chem. Biol. 2014, 10, 574-581

"Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA"

 

Link to publication

183

N. Kitsera, K. Gasteiger, B. Lühnsdorf, J. Allgayer, B. Epe, T. Carell, A. Khobta

PLOS One 2014, 9(4), e94405

"Cockayne Syndrome: Varied Requirement of Transcription-Coupled Nucleotide Excision Repair for the Removal of Three Structurally Different Adducts from Transcribed DNA"

 

Link to publication

182

S. Serdjukow, F. Kink, B. Steigenberger, M. Tomas–Gamasa, T. Carell

Chem. Commun. 2014, 50, 1861-1863

"Synthesis of γ-labeled nucleoside 5'-triphosphates using click chemistry"

 

Link to publication

181

D.B. Bucher, B.M. Pilles, T. Carell, W. Zinth

Proc. Natl. Acad. Sci. USA, 2014, 111(12), 4369-4374

"Charge separation and charge delocalization identified in long-living states of photoexcited DNA"

 

Link to publication

180

P. Bashtrykov, A. Rajavelu, B. Hackner, S. Ragozin, T. Carell, A. Jeltsch

ChemBioChem, 2014, 15, 743-8

"Targeted Mutagenesis Results in an Activation of DNA Methyltransferase 1 and Confirms an Autoinhibitory Role of its RFTS Domain"

 

Link to publication

179

D.B. Bucher, B.M. Pilles, T. Pfaffeneder, T. Carell, W. Zinth

Chemphyschem, 2014, 15, 420-3

"Fingerprinting DNA oxidation processes: IR characterization of the 5-methyl-2´-deoxycytidine radical cation"

 

Link to publication

178

C.N. Buechner, K. Heil, G. Michels, T. Carell, C. Kisker, I. Tessmer

J. Biol. Chem. 2014, 289, 3613-3624

"Strand specific recognition of DNA damages by XPD provides insights into Nucleotide Excision Repair substrate versatility"

 

Link to publication

177

M. Su, M. Tomás-Gamasa, S. Serdjukow, P. Mayer, T. Carell

Chem. Commun. (Camb.) 2014, 50, 409-411

"Synthesis and properties of a Cu(II) complexing pyrazole ligandoside in DNA"

 

Link to publication

176

A.S. Schröder, J. Steinbacher, B. Steigenberger, F.A. Gnerlich, S. Schiesser, T. Pfaffeneder, T. Carell

Angew. Chem. Int. Ed. 2014, 53, 315-8 (selected as Hot-Paper)

"Synthesis of a DNA Promoter Segment Containing All Four Epigenetic Nucleosides: 5-Methyl-, 5-Hydroxymethyl-, 5-Formyl-, and 5-Carboxy-2’-Deoxycytidine"

 

Link to publication

175

A.C. Kneuttinger, G. Kashiwazaki, S. Prill, K. Heil, M. Müller, T. Carell

Photochem. Photobiol. 2014, 90, 1-14

"Formation and Direct Repair of UV-induced Dimeric DNA Pyrimidine Lesions"

 

Link to publication

2013 – Ludwig-Maximilians-Universität München (Germany)

174

I. Thoma, T. Carell

Eur. J. Org. Chem. 2013, 21, 4483-85

"Total Synthesis of the Hypermodified tRNA Nucleoside Epoxyqueuosine"

 

Link to publication

173

M. Vrabel, P. Kölle, K.M. Brunner, M.J. Gattner, V. López-Carillo, R. de Vivie-Riedle, T. Carell

Chemistry, 2013, 19, 13309-12

"Norbornenes in Inverse Electron-Demand Diels-Alder Reactions"

 

Link to publication

172

S. Schneider, M.J. Gattner, M. Vrabel, V. Flügel, V. López-Carillo, S. Prill, T. Carell

ChemBioChem, 2013, 14, 2114-8

"Structural Insights into Incorporation of Norbornene Amino Acids for Click Modification of Proteins"

 

Link to publication

171

S. Schiesser, T. Pfaffeneder, K. Sadeghian, B. Hackner, B. Steigenberger, A.S. Schröder, J. Steinbacher, G. Kashiwazaki, G. Höfner, K.T. Wanner, C. Ochsenfeld, T. Carell

J. Am. Chem. Soc. 2013, 135, 14593-9

"Deamination, Oxidation and C-C bond Cleavage Reactivity of 5-Hydroxymethylcytosine, 5-Formylcytosine and 5-Carboxycytosine"

 

Link to publication

170

M. Shehata, J. Durner, A. Eldenez, K. Van Landuyt, P. Styllou, L. Rothmund, R. Hickel, H. Scherthan, W. Geurtsen, B. Kaina, T. Carell, F.X. Reichl

Dent. Mater. 2013, 29, 971-9

"Cytotoxicity and induction of DNA double-strand breaks by components leached from dental composites in primary human gingival fibroblasts"

 

Link to publication

169

K. Groll, S.M. Manolikakes, X.M. du Jourdin, M. Jaric, A. Bredihhin, K. Karaghiosoff, T. Carell, P. Knochel

Angew. Chem. Int. Ed. 2013, 52, 6776-80

"Regioselective Metalations of Pyrimidines and Pyrazines by Using Frustrated Lewis Pairs of BF3-OEt2 and Hindered Magnesium- and Zinc-Amide Bases"

 

Link to publication

168

T.H. Gehrke, U. Lischke, K.L. Gasteiger, S. Schneider, S. Arnold, H.C. Müller, D.S. Stephenson, H. Zipse T. Carell

Nature Chem. Biol. 2013, 9, 455-61

"Unexpected non-Hoogsteen-based mutagenicity mechanism of FaPy-DNA lesions"

 

Link to publication

167

C.G. Spruijt, F. Gnerlich, A.H. Smits, T. Pfaffeneder, P.W.T.C. Jansen, C. Bauer, M. Münzel, M. Wagner, M. Müller, F. Khan, H.C. Eberl, A. Mensinga, A.B. Brinkman, K. Lephikov, U. Müller, J. Walter, R. Boelens, H. van Ingen, H. Leonhardt, T. Carell∗, M. Vermeulen∗

Cell 2013, 152, 1146-59.

"Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives"

 

Link to publication

166

A. Hienzsch, C. Deiml, V. Reiter, T. Carell

Chemistry 2013, 19, 4244-8.

"Total Synthesis of the Hypermodified RNA Bases Wybutosine and Hydroxywybutosine and Their Quantification Together with Other Modified RNA Bases in Plant Materials"

 

Link to publication

165

B. Steigenberger, S. Schiesser, B. Hackner, C. Brandmayr, S.K. Laube, J. Steinbacher, T. Pfaffeneder, T. Carell

Org. Lett. 2013, 15, 366-369.

"Synthesis of 5-Hydroxymethyl-, 5-Formyl-, and 5-Carboxycytidine-triphosphates and Their Incorporation into Oligonucleotides by Polymerase Chain Reaction"

 

Link to publication

164

M. Ehrlich, T. Carell

Eur. J. Org. Chem. 2013, 1, 77-83.

"Total Syntheses and Biological Evaluation of 3-O-Methylfunicone and Its Derivatives Prepared by TMPZnCl·LiCl-Mediated Halogenation and Carbonylative Stille Cross-Coupling"

 

Link to publication

163

A.C. Kneuttinger, K. Heil, G. Kashiwazaki, T. Carell

Chem. Commun. (Camb.) 2013, 49, 722-724

"The Radical SAM Enzyme Spore Photoproduct Lyase Employs a Tyrosyl Radical for DNA Repair"

 

Link to publication

162

M.J. Gattner, M. Vrabel, T. Carell

Chem. Commun. (Camb.) 2013, 49, 379-381

"Synthesis of ε-N-propionyl-, ε-N-butyryl-, and ε-N-crotonyl-lysine containing histone H3 using the pyrrolysine system"

 

Link to publication

2012 – Ludwig-Maximilians-Universität München (Germany)

161

C. Brandmayr, M. Wagner, T. Brückl, D. Globisch, D. Pearson, A.C. Kneuttinger, V. Reiter, A. Hienzsch, S. Koch, I. Thoma, P. Thumbs, S. Michalakis, M. Müller, M. Biel, T. Carell

Angew. Chem. Int. Ed. 2012, 51, 11162-5.

Isotope-Based Analysis of Modified tRNA Nucleosides Correlates Modification Density with Translational Efficiency

 Link to publication

160

T.F. Kraus, D. Globisch, M. Wagner, S. Eigenbrod, D. Widmann, M. Münzel, M. Müller, T. Pfaffeneder, B. Hackner, W. Feiden, U. Schüller, T. Carell, H.A. Kretzschmar

Int. J. Cancer. 2012, 131, 1577-90.

Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base" are associated with anaplasia in human brain tumors

 

Link to publication

159

J. Willibald, J. Harder, K. Sparrer, K.-K. Conzelmann, T. Carell

J. Am. Chem. Soc. 2012, 134, 12330-3.

Click Modified Anandamide siRNA Enables Delivery and Gene Silencing in Neuronal and Immune Cells

 

Link to publication

 

158

J. Timper, K. Gutsmiedl, C. Wirges, J. Broda, M. Noyong, J. Mayer, T. Carell, U. Simon

Angew. Chem. Int. Ed. 2012, 51, 7586-8.

Surface "Click" Reaction of DNA followed by Directed Metalization for the Construction of Contactable Conducting Nanostructures

 

Link to publication

157

T. Carell, C. Brandmayr, A. Hienzsch, M. Müller, D. Pearson, V. Reiter, I. Thoma, P. Thumbs, M. Wagner,

Angew. Chemie. Int. Ed. 2012, 51, 7110-7131.

Structure and Function of Noncanonical Nucleobases

 

Link to publication

156

A. Benjdia, K. Heil, T. R. Barends, T. Carell, I. Schlichting

Nucleic Acids Res. 2012, 40, 9308-18

Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme

 

Link to publication

155

V. Reiter, D. M. S. Matschkal, M. Wagner, D. Globisch, A. C. Kneuttinger, M. Müller, T. Carell

Nucleic Acids Res. 2012, 40, 6235-6240.

The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA

 

Link to publication

154

S. Schiesser, P. Mayer, T. Carell, W. Beck

Z. Naturforsch. 2012, 67b, 849-852.

Molecular and Crystal Structure of Potassium-l-alaninato-dichloridoplatinate(II), K[Pt(l-alaO)Cl2]

 

Link to publication

153

S. Schiesser, B. Hackner, T. Pfaffeneder, M. Müller, C. Hagemeier, M. Truss, T. Carell

Angew. Chemie. Int. Ed. 2012, 51, 6516-6520.

Mechanism and Stem-Cell Activity of 5-Carboxycytosine Decarboxylation Determined by Isotope Tracing

 

Link to publication

152

B.P. Fingerhut, S. Oesterling, K. Haiser, K. Heil, A. Glas, W.J. Schreier, W. Zinth, T. Carell, R. de Vivie-Riedle

J. Chem. Phys. 2012, 136, 204307.

ONIOM approach for non-adiabatic on-the-fly molecular dynamics demonstrated for the backbone controlled dewar valence isomerization

 

Link to publication

151

E. Kaya, M. Vrabel, C. Deiml, S. Prill, V. S. Fluxa, T. Carell.

Angew. Chem. Int. Ed. 2012, 51, 4466-9.

A Genetically encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-free Click Reaction

 

Link to publication

150

C. Walmacq, A.C. Cheung, M.L. Kireeva, L. Lubkowska, C. Ye, D. Gotte, J. N. Strathern, T. Carell, P. Cramer, M. Kashlev

Mol. Cell. 2012, 46, 18-29.

Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage

 

Link to publication

149

D. Stathis, U. Lischke, S. C. Koch, C. A. Deiml, T. Carell

J. Am. Chem. Soc. 2012, 134, 4925-30.

Discovery and Mutagenicity of a Guanidinoformimine Lesion as a new Intermediate of the Oxidative Deoxyguanosine Degradation Pathway

 

Link to publication

148

K. Haiser, B. P. Fingerhut, K. Heil, A. Glas, T. T. Herzog, B. M. Pilles, W. J. Schreier, W. Zinth, R. de Vivie-Riedle, T. Carell

Angew. Chem. Int. Ed. 2012, 51, 408-11.

Mechanism of UV-Induced Formation of Dewar Lesions in DNA

 

Link to publication

147

N. Diamant, A. Hendel, I. Vered, T. Carell, T. Reissner, N. de Wind, N. Geacinov, Z. Livneh

Nucleic Acids Res. 2012, 40, 170-80.

DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity

 

Link to publication

2011 – Ludwig-Maximilians-Universität München (Germany)

146

M. Münzel, U. Lischke, D. Stathis, T. Pfaffeneder, F. A. Gnerlich, C. A. Deiml, S. C. Koch, K. Karaghiosoff, T. Carell

Chemistry 2011, 17, 13782-13788.

Selected as News Item in "Chemistry Views" on 22 November 2011 Improved Synthesis and Mutagenicity of Oligonucleotides Containing 5-Hydroxymethylcytosine, 5-Formylcytosine and 5-Carboxylcytosine

 

Link to publication

145

F. Civril, M. Bennett, M. Moldt, T. Deimling, G. Witte, S. Schiesser, T. Carell, K. P. Hopfner

EMBO Rep. 2011, 12, 1127-34.

The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling

 

Link to publication

144

D. Globisch, D. Pearson, A. Hienzsch, T. Brückl, M. Wagner, I. Thoma, P. Thumbs, V. Reiter, A. Kneuttinger, M. Müller, S. Sieber, T. Carell

Angew. Chem. Int. Ed. 2011, 50, 9739-9742.

Systems-Based Analysis of Modified tRNA Bases

 

Link to publication

143

J. Fei, N. Kaczmarek, A. Luch, A. Glas, T. Carell, H. Naegeli

PLoS Biol. 2011, 9, e1001183.

Regulation of Nucleotide Excision Repair by UV-DDB: Prioritization of Damage Recognition to Internucleosomal DNA

 

Link to publication

142

S. Kiontke, Y. Geisselbrecht, R. Pokorny, T. Carell, A. Batschauer, L. O. Essen

EMBO J. 2011, 30, 4437-49.

Crystal structures of an archaeal class II DNA photolyase and its complex with UV-damaged duplex DNA

 

Link to publication

141

A. Hendel, P. H. Krijger, N. Diamant, Z. Goren, P. Langerak, J. Kim, T. Reissner, K. Y. Lee, N. E. Geacintov, T. Carell K. Myung, S. Tateishi, A. D’Andrea, H. Jacobs, Z. Livneh

PLoS Genet. 2011, 7, e1002262.

PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells

 

Link to publication

140

C. Kaul, M. Müller, M. Wagner, S. Schneider, T. Carell

Nature Chem. 2011, 3, 794-800.

Reversible bond formation enables replication and amplification of a crosslinking salen complex as an orthogonal base pair

 

Link to publication

139

M. Vrabel, E. Kaya, S. Prill, V. Ehmke, T. Carell

Collect. Czech. Chem. Commun. 2011, 76, 1089-1101.

Optimization of the posttranslational click modification of proteins

 

Link to publication

138

K. Heil, A. C. Kneuttinger, S. Schneider, U. Lischke, T. Carell

Chemistry 2011, 17, 9651-7.

Crystal Structures and Repair Studies Reveal the Identity and the Base-Pairing Properties of the UV-Induced Spore Photoproduct DNA Lesion

 

Link to publication

137

A. Stadler, J. O. Delos Santos, E. S. Stensrud, A. Dembska, G. L. Silva, S. Liu, N. I. Shank, E. Kunttas-Tatli, C. J. Sobers, P. M. E. Gramlich, T. Carell, L. A. Peteanu, B. M. McCartney, B. A. Armitage

Bioconjug. Chem. 2011, 22, 1491-502.

Fluorescent DNA Nanotags Featuring Covalently Attached Intercalating Dyes: Synthesis, Antibody Conjugation, and Intracellular Imaging

 

Link to publication

136

K. Heil, D. Pearson, T. Carell

Chem. Soc. Rev. 2011, 40, 4271-8.

Chemical investigation of light induced DNA bipyrimidine damage and repair

 

Link to publication

135

Y. V. Le Bihan, M. Angeles Izquierdo, F. Coste, P. Aller, F. Culard, T. H. Gehrke, K. Essalhi, T. Carell, B. Castaing

Nucleic Acids Res. 2011, 39, 6277-90.

5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases

 

Link to publication

134

N. Kitsera, D. Stathis, B. Lühnsdorf, H. Müller, T. Carell, B. Epe, A. Khobta

Nucleic Acids Res. 2011, 39, 5926-34.

8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1

 

Link to publication

133

T. Pfaffeneder, B. Hackner, M. Truss, M. Münzel, M. Müller, C. A. Deiml, C. Hagemeier, T. Carell

Angew. Chem. Int. Ed. 2011, 50, 7008-12.

The discovery of 5-formylcytosine in embryonic stem cell DNA

 

Link to publication

132

M. Münzel, D. Globisch, T. Carell

Angew. Chem. Int. Ed. 2011, 50, 6460-8.

5-Hydroxymethylcytosine, the sixth base of the genome

 

Link to publication

131

D. Pearson, T. Carell

Nucleic Acids Res. 2011, 39, 4818-26.

Assay of both activities of the bifunctional tRNA-modifying enzyme MnmC reveals a kinetic basis for selective full modification of cmnm5s2U to mnm5s2U

 

Link to publication

130

D. Pearson, A. Hienzsch, M. Wagner, D. Globisch, V. Reiter, D. Özden, T. Carell

Chem. Commun. (Camb.) 2011, 47, 5196-8.

LC-MS based quantification of 2′-ribosylated nucleosides Ar(p) and Gr(p) in tRNA

 

Link to publication

129

M. Münzel, C. Szeibert, A. F. Glas, D. Globisch, T. Carell

J. Am. Chem. Soc. 2011, 133, 5186-9.

Discovery and synthesis of new UV-induced intrastrand C(4-8)G and G(8-4)C photolesions

 

Link to publication

128

M. Wenninger, D. Fazio, U. Megerle, C. Trindler, S. Schiesser, E. Riedle, T. Carell

ChemBioChem 2011, 12, 703-6.

Flavin-induced DNA photooxidation and charge movement probed by ultrafast transient absorption spectroscopy

 

Link to publication

127

S. Zimdars, X. Mollat du Jourdin, F. Crestey, T. Carell, P. Knochel

Org. Lett. 2011, 13, 792-795.

Trifunctionalization of the Purine Scaffold Using Mg and Zn Organometallic Intermediates

 

Link to publication

126

D. Fazio, C. Trindler, K. Heil, C. Chatgilialoglu, T. Carell

Chemistry 2011, 17, 206-212.

Investigation of Excess-Electron Transfer in DNA Double-Duplex Systems Allows Estimation of Absolute Excess-Electron Transfer and CPD Cleavage Rates

 

Link to publication

2010 – Ludwig-Maximilians-Universität München (Germany)

125

D. Globisch, M. Münzel, M. Müller, S. Michalakis, M. Wagner, S. Koch, T. Brückl, M. Biel, T. Carell

PLoS One 2010, 5, e15367.

Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates

 

Link to publication

124

M. Münzel, D. Globisch, C. Trindler, T. Carell

Org. Lett. 2010, 12, 5671-5673.

Efficient Synthesis of 5-Hydroxymethylcytosine Containing DNA

 

Link to publication

123

S. Schorr, T. Carell

ChemBioChem 2010, 11, 2534-2537.

Mechanism of Acetylaminofluorene-dG Induced Frameshifting by Polymerase η

 

Link to publication

122

S. Schorr, S. Schneider, K. Lammens, K.-P. Hopfner, T. Carell

Proc. Natl. Acad. Sci. USA 2010, 107, 20720-20725.

Mechanism of replication blocking and bypass of Y-family polymerase η by bulky acetylaminofluorene DNA adducts

 

Link to publication

121

M. Münzel, L. Lercher, M. Müller, T. Carell

Nucleic Acids Res. 2010, 38, e192.

Chemical discrimination between dC and 5MedC via their hydroxylamine adducts

 

Link to publication

120

S. Schneider, T. Reissner, O. Ziv, Z. Livneh, T. Carell

ChemBioChem 2010, 11, 1521-4.

Translesion synthesis of 1,3-GTG cisplatin DNA lesions

 

Link to publication

119

T. Brückl, I. Thoma, A. J. Wagner, P. Knochel, T. Carell

Eur. J. Org. Chem. 2010, 2010, 6517-6519.

Efficient Synthesis of Deazaguanosine-Derived tRNA Nucleosides PreQ0, PreQ1, and Archaeosine Using the Turbo-Grignard Method

 

Link to publication

118

M. Münzel, D. Globisch, T. Brückl, M. Wagner, V. Welzmiller, S. Michalakis, M. Müller, M. Biel, T. Carell

(Selected as Hot Paper and Highlighted in a Science and Technology Concentrate in Chem. Eng. News 2010, 88 (No 27), 24.)

Angew. Chem. Int. Ed. 2010, 49, 5375-5377.

Quantification of the Sixth DNA Base Hydroxymethylcytosine in the Brain

 

Link to publication

117

G. H. Clever, J. Reitmeier, T. Carell, O. Schiemann

(Selected as Hot Paper and Highlighted in a Science and Technology Concentrate in Chem. Eng. News 2010, 88 (No 27), 24.)

Angew. Chem. Int. Ed. 2010, 49, 4927-4929.

Antiferromagnetic Coupling of Stacked CuII-Salen Complexes in DNA

 

Link to publication

116

M. Winnacker, V. Welzmiller, R. Strasser, T. Carell

ChemBioChem 2010, 11, 1345-1349.

Development of a DNA Photoaffinity Probe for the Analysis of 8-OxodG-Binding Proteins in a Human Proteome

 

Link to publication

115

A. Schlossbauer, S. Warncke, P. E. Gramlich, J. Kecht, A. Manetto, T. Carell, T. Bein

Angew. Chem. Int. Ed. 2010, 49, 4734-4737.

A Programmable DNA-Based Molecular Valve for Colloidal Mesoporous Silica

 

Link to publication

114

K. Gutsmiedl, D. Fazio, T. Carell

Chemistry 2010, 16, 6877-6883.

High-Density DNA Functionalization by a Combination of Cu-Catalyzed and Cu-Free Click Chemistry

 

Link to publication

113

T. Reißner, S. Schneider, S. Schorr, T. Carell

Angew. Chem. Int. Ed. 2010, 49, 3077-3080.

Crystal Structure of a Cisplatin-(1,3-GTG) Cross-Link within DNA Polymerase η

 

Link to publication

112

A. F. Glas, E. Kaya, S. Schneider, K. Heil, D. Fazio, M. J. Maul, T. Carell

J. Am. Chem. Soc. 2010, 132, 3254-3255.

DNA (6-4) Photolyases Reduce Dewar Isomers for Isomerization into (6-4) Lesions

 

Link to publication

2009 – Ludwig-Maximilians-Universität München (Germany)

111

E. Kaya, K. Gutsmiedl, M. Vrabel, M. Müller, P. Thumbs, T. Carell

ChemBioChem 2009, 10, 2858-2861.

"Synthesis of threefold glycosylated proteins using click chemistry and genetically encoded unnatural amino acids"

 

Link to publication

110

B. M. Gaub, C. Kaul, J. L. Zimmermann, T. Carell, H. E. Gaub

Nanotechnolog, 2009, 20, 434002.

"Switching the mechanics of dsDNA by Cu salicylic aldehyde complexation"

 

Link to publication

109

A. F. Glas, S. Schneider, M. J. Maul, U. Hennecke, T. Carell

Chemistry 2009, 15, 10387-10396.

"Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of UV-Induced (6-4) and Dewar Photolesions"

 

Link to publication

108

A. F. Glas, M. J. Maul, M. Cryle, T. R. M. Barends, S. Schneider, E. Kaya, I. Schlichting, T. Carell

Proc. Natl. Acad. Sci. USA 2009, 106, 11540-11545.

"The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes"

 

Link to publication

107

C. Trindler, A. Manetto, J. Eirich, T. Carell

Chem. Commun. (Camb.) 2009, 24, 3583-3584.

"A new ground state single electron donor for excess electron transfer studies in DNA"

 

Link to publication

106

K. Gutsmiedl, C. T. Wirges, V. Ehmke, T. Carell

Org. Lett. 2009, 11, 2405-2408.

"Copper-Free "Click" Modification of DNA via Nitrile Oxide-Norbornene 1,3-Dipolar Cycloaddition"

 

Link to publication

105

M. Müller, T. Carell

Curr. Opin. Struct. Biol. 2009, 19, 277-285.

"Structural biology of DNA photolyases and cryptochromes"

 

Link to publication

104

S. Warncke, A. Gégout, T. Carell

ChemBioChem 2009, 10, 728-734.

"Phosphorothioation of Oligonucleotides Strongly Influences the Inhibition of Bacterial (M.HhaI) and Human(Dnmt1) DNA Methyltransferases"

 

Link to publication

103

S. Shachar, O. Ziv, S. Avkin, S. Adar, J. Wittschieben, T. Reißner, S. Chaney, E. C. Friedberg, Z. Wang, T. Carell, N. Geacintov, Z. Livneh

EMBO J. 2009, 28, 383-393.

"Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals"

 

Link to publication

102

S. Schneider, S. Schorr, T. Carell

Curr. Opin. Struct. Biol. 2009, 19, 87-95.

"Crystal structure analysis of DNA lesion repair and tolerance mechanisms"

 

Link to publication

101

M. Winnacker, S. Breeger, R. Strasser, T. Carell

ChemBioChem 2009, 10, 109-118.

"Novel Diazirine-Containing DNA Photoaffinity Probes for the Investigation of DNA-Protein-Interactions"

 

Link to publication

100

MT. Brückl, D. Globisch, M. Wagner, M. Müller, T. Carell (Selected as Hot Paper and Highlighted in a Science and Technology Concentrate in Chem. Eng. News, 2009, 87 (No 38), 35.)

Angew. Chem. Int. Ed. 2009, 48, 7932-7934.

"Parallel Isotope-Based Quantification of Modified tRNA Nucleosides"

 

Link to publication

99

T. Reißner, S. Schorr, T. Carell

Angew. Chem. Int. Ed. (Highlight), 2009, 48, 7293-7295.

"Once Overlooked, Now Made Visible: ATL Proteins and DNA Repair"

 

Link to publication

98

C. T. Wirges, J. Timper, M. Fischler, A. S. Sologubenko, J. Mayer, U. Simon, T. Carell

Angew. Chem. Int. Ed. (Highlight), 2009, 48, 219-223.

"Controlled Nucleation of DNA Metallization"

Link to publication

2008 – Ludwig-Maximilians-Universität München (Germany)

97

R. Pokorny, T. Klar, U. Hennecke, T. Carell, A. Batschauer, L. O. Essen

Proc. Natl. Acad. Sci. USA 2008, 105,21023-21027.

Recognition and repair of UV lesions in loop structures of duplex DNA by DASH-type cryptochrome

 

Link to publication

96

E. Bürckstümmer, T. Carell

Chem. Commun. (Camb). 2008, 34,4037-4039.

Synthesis and properties of DNA containing a spore photoproduct analog

 

Link to publication

95

F. Coste, M. Ober, Y.-V. Le Bihan, M. A. Izquierdo, N. Hervouet, H. Mueller, T. Carell, B. Castaing

Chem. Biol. 2008, 15,706-717.

Bacterial Base Excision Repair Enzyme Fpg Recognizes Bulky N7-Substituted-FapydG Lesion via Unproductive Binding Mode

 

Link to publication

94

H. Müller, M. Hopfinger, T. Carell

ChemBioChem 2008, 9,1617-1622.

Synthesis of a Stabilized Version of the Imidazolone DNA Lesion

 

Link to publication

93

P. M. E. Gramlich, C. T. Wirges, J. Gierlich, T. Carell

Org. Lett. 2008, 10,249-251.

Synthesis of Modified DNA by PCR with Alkyne-Bearing Purines Followed by a Click Reaction

 

Link to publication

92

M. Fischler, A. Sologubenko, J. Mayer, G. Clever, G. A. Burley, J. Gierlich, T. Carell, U. Simon

Chem. Commun. (Camb.) 2008, 169-171.

Chain-like assembly of gold nanoparticles on artificial DNA templates via "click chemistry"

 

Link to publication

91

M. J. Maul, T. R. M. Barends, A. F. Glas, M. J. Cryle, T. Domratcheva, S. Schneider, I. Schlichting, T. Carell

Angew. Chem. Int. Ed. 2008, 47,10076-10080.

Crystal Structure and Mechanism of a DNA (6-4) Photolyase

 

Link to publication

90

P. M. E. Gramlich, C. T. Wirges, A. Manetto, T. Carell

Angew. Chem. Int. Ed. 2008, 47,8350-8358.

Postsynthetic DNA Modification through the Copper-Catalyzed Azide-Alkyne Cycloaddition Reaction

 

Link to publication

89

P. M. E. Gramlich, S. Warncke, J. Gierlich, T. Carell

Angew. Chem. Int. Ed. 2008, 47,3442-3444.

Click-Click-Click: Single to Triple Modification of DNA

 

Link to publication

88

D. Kuch, L. Schermelleh, S. Manetto, H. Leonhardt, T. Carell

Angew. Chem. Int. Ed. 2008, 47,1515-1518.

Synthesis of DNA Dumbbell Based Inhibitors for the Human DNA Methyltransferase Dnmt1

 

Link to publication

87

S. Bareyt, T. Carell

Angew. Chem. Int. Ed. 2008, 47,181-184.

Selective Detection of 5-Methylcytosine Sites in DNA

 

Link to publication

86

F. Büsch, J. C. Pieck, M. Ober, J. Gierlich, G. W. Hsu, L. S. Beese, T. Carell

Chemistry 2008, 14,2125-2132.

Dissecting the Differences between the αand β Anomers of the Oxidative DNA Lesion FaPydG

 

Link to publication

2007 – Ludwig-Maximilians-Universität München (Germany)

85

T. Brückl, F. Klepper, K. Gutsmiedl, T. Carell

Org. Biomol. Chem. 2007, 5,3821-3825.

A short and efficient synthesis of the tRNA nucleosides PreQ0 and archaeosine

 

Link to publication

84

G. E. Damsma, A. Alt, F. Brueckner, T. Carell, P. Cramer

Nat. Struct. Mol. Biol. 2007, 14,1127-1133.

Mechanism of transcriptional stalling at cisplatin-damaged DNA

 

Link to publication

83

A. Alt, K. Lammens, C. Chiocchini, A. Lammens, J. C. Pieck, D. Kuch, K.-P. Hopfner, T. Carell

Science 2007, 318, 967-970.

Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase η

 

Link to publication

82

D. I. Rozkiewicz, J. Gierlich, G. A. Burley, K. Gutsmiedl, T. Carell, B. J. Ravoo, D. N. Reinhoudt

ChemBioChem 2007, 8,1997-2002.

Transfer Printing of DNA by "Click" Chemistry

 

Link to publication

81

M. Fischler, U. Simon, H. Nir, Y. Eichen, G. A. Burley, J. Gierlich, P. M. E. Gramlich, T. Carell

Small 2007, 3, 1049-1055.

Formation of Bimetallic Ag-Au Nanowires by Metallization of Artificial DNA Duplexes

 

Link to publication

80

A. Manetto, D. Georganakis, L. Leondiadis, T. Gimisis, P. Mayer, T. Carell, C. Chatgilialoglu

J. Org. Chem. 2007, 72, 3659-3666.

Independent Generation of C5′-Nucleosidyl Radicals in Thymidine and 2′-Deoxyguanosine

 

Link to publication

79

C. T. Wirges, P. M. E. Gramlich, K. Gutsmiedl, J. Gierlich, G. A. Burley, T. Carell

QSAR Comb. Sci. 2007, 26, 1159-1164.

Pronounced Effect of DNA Hybridization on Click Reaction Efficiency

 

Link to publication

78

F. Spada, A. Haemmer, D. Kuch, U. Rothbauer, L. Schermelleh, E. Kremmer, T. Carell, G. Längst, H. Leonhardt

J. Cell Biol. 2007, 176, 565

DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells

 

Link to publication

77

F. Brueckner, U. Hennecke, T. Carell, P. Cramer

Science 2007, 315, 859-862.

CPD Damage Recognition by Transcribing RNA Polymerase II

 

Link to publication

76

H. Müller, T. Carell

Eur. J. Org. Chem. 2007, 9, 1438-1445.

A Carbocyclic Analog of the Oxidatively Generated DNA Lesion Spiroiminodihydantoin

 

Link to publication

75

W. J. Schreier, T. E. Schrader, F. O. Koller, P. Gilch, C. E. Crespo-Hernández, V. N. Swaminathan, T. Carell, W. Zinth, B. Kohler

Science 2007, 315, 625-629.

Thymine Dimerization in DNA is an Ultrafast Photoreaction

 

Link to publication

74

G. H. Clever, C. Kaul, T. Carell

Angew. Chem. Int. Ed. 2007, 46, 6226-6236.

DNA-metal base pairs

 

Link to publication

73

D. M. Hammond, A. Manetto, J. Gierlich, V. A. Azov, P. M. E. Gramlich, G. A. Burley, M. Maul, T. Carell

Angew. Chem. Int. Ed. 2007, 46, 4184-4187.

DNA Photography: An Ultrasensitive DNA-Detection Method Based on Photographic Techniques

 

Link to publication

72

U. Hennecke, D. Kuch, T. Carell

Synthesis, 2007, 6, 929-935.

A General Route to 4-C-Substituted Pyrimidine Nucleosides

 Link to publication

71

F. Klepper, E.-M. Jahn, V. Hickmann, T. Carell

Angew. Chem. Int. Ed. 2007, 46, 2325-2327.

Synthesis of the Transfer-RNA Nucleoside Queuosine by Using a Chiral Allyl Azide Intermediate

 

Link to publication

70

G. H. Clever, T. Carell

Angew. Chem. Int. Ed. 2007, 46, 250-253.

Controlled Stacking of 10 Transition-Metal Ions inside a DNA Duplex

 

Link to publication

69

J. Gierlich, K. Gutsmiedl, P. M. E. Gramlich, A. Schmidt, G. A. Burley, T. Carell

Chemistry 2007, 13, 9486-9494.

Synthesis of Highly Modified DNA by a Combination of PCR with Alkyne-Bearing Triphosphates and Click Chemistry

 

Link to publication

68

C. Chatgilialoglu, M. Guerra, P. Kaloudis, C. Houée-Lévin, J. L. Marignier, V. N. Swaminathan, T. Carell

Chemistry 2007, 13, 8979-8984.

Ring Opening of the Cyclobutane in a Thymine Dimer Radical Anion

 

Link to publication

2006 – Ludwig-Maximilians-Universität München (Germany)

66

K. Tanaka, G. H. Clever, Y. Takezawa, Y. Yamada, C. Kaul, M. Shionoya, T. Carell

Nature Nanotechnol. 2006, 1, 190-194.

Programmable self-assembly of metal ions inside artificial DNA duplexes

 

Link to publication

65

G. H. Clever, Y. Soltl, H. Burks, W. Spahl, T. Carell

Chemistry 2006, 12, 8708.

Metal-Salen-Base-Pair Complexes Inside DNA: Complexation Overrides Sequence Information

 

Link to publication

64

J. C. Pieck, U. Hennecke, A. J. Pierik, M. G. Friedel, T. Carell

J. Biol. Chem. 2006, 281, 36317.

Characterization of a New Thermophilic Spore Photoproduct Lyase from Geobacillus stearothermophilus (SplG) with Defined Lesion Containing DNA Substrates

 

Link to publication

63

T. Klar, G. Kaiser, U. Hennecke, T. Carell, A. Batschauer, L. O. Essen

ChemBioChem 2006, 7, 1798.

Natural and Non-natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus

 

Link to publication

62

S. Breeger, M. von Meltzer, U. Hennecke, T. Carell

Chemistry 2006, 12, 6469-6477.

Investigation of the pathways of excess electron transfer in DNA with flavin-donor and oxetane-acceptor modified DNA hairpins

 

Link to publication

61

J. Gierlich, G. A. Burley, P. M. E. Gramlich, D. M. Hammond, T. Carell

Org. Lett. 2006, 8, 3639-3642.

Click Chemistry as a Reliable Method for the High-Density Postsynthetic Functionalization of Alkyne-Modified DNA

 

Link to publication

60

M. G. Friedel, J. C. Pieck, J. Klages, C. Dauth, H. Kessler, T. Carell

Chemistry 2006, 12, 6081-6094.

Synthesis and Stereochemical Assignment of DNA Spore Photoproduct Analogues

 

Link to publication

59

J. C. Pieck, D. Kuch, F. Grolle, U. Linne, C. Haas, T. Carell

J. Am. Chem. Soc. 2006, 128, 1404-1405.

PNA-Based Reagents for the Direct and Site-Specific Synthesis of Thymine Dimer Lesions in Genomic DNA

 

Link to publication

58

G. A. Burley, J. Gierlich, M. R. Mofid, H. Nir, S. Tal, Y. Eichen, T. Carell

J. Am. Chem. Soc. 2006, 128, 1398-1399.

Directed DNA Metallization

 

Link to publication

57

M. G. Friedel, O. Berteau, J. C. Pieck, M. Atta, S. Ollagnier-de-Choudens, M. Fontecave. T. Carell

Chem. Commun. (Camb.) 2006, 445-447.

The spore photoproduct lyase repairs the 5S- and not the 5R-configured spore photoproduct DNA lesion

 

Link to publication

2005 – Ludwig-Maximilians-Universität München (Germany)

56

M. Ober, H. Müller, C. Pieck, J. Gierlich, T. Carell

J. Am. Chem. Soc. 2005, 127, 18143-18149.

Base Pairing and Replicative Processing of the Formamidopyrimidine-dG DNA Lesion

 

Link to publication

55

A. Manetto, S. Breeger, C. Chatgilialoglu, T. Carell

Angew. Chem. Int. Ed. 2005, 45, 318-321.

Complex Sequence Dependence by Excess-Electron Transfer through DNA with Different Strength Electron Acceptors

 

Link to publication

54

G. H. Clever, K. Polborn, T. Carell

Angew. Chem. Int. Ed. 2005, 44, 7204-7208.

A Highly DNA-Duplex-Stabilizing Metal-Salen Base Pair

 

Link to publication

53

F. Klepper, K. Polborn, T. Carell

Helv. Chim. Acta 2005, 88, 2610-2616.

Robust synthesis and crystal-structure analysis of 7-cyano-7-deazaguanine (PreQ0 base) and 7-(aminomethyl)-7-deazaguanine (PreQ1 base)

 

Link to publication

52

M. G. Friedel, M. K. Cichon, T. Carell

Org. Biomol. Chem. 2005, 3, 1937-1941.

Model compounds for (6-4) photolyases: a comparative flavin induced cleavage study of oxetanes and thietanes

 

Link to publication

51

M. v. Meltzer, M. Marsch, T. Carell, K. Harms

Acta. Cryst. E. 2005, 3, 1937-1941.

(1S,2R,4R,5R)-tert-Butyl N-(4-hydroxymethyl-6-oxabicyclo[3.1.0]hex-2-yl)carbamate

 

Link to publication

2004 – Ludwig-Maximilians-Universität München (Germany)

50

A. Mees, T. Klar, P. Gnau, U. Hennecke, A. P. M. Eker, T. Carell and L.-O. Essen

Science 2004, 306, 1789-1793.

Crystal Structure of a Photolyase Bound to a CPD-Like DNA Lesion After in Situ Repair

 

Link to publication

49

L. M. Kundu, U. Linne, M. Marahiel, T. Carell

Chemistry 2004, 10, 5697-5705.

RNA Is More UV Resistant than DNA: The Formation of UV-Induced DNA Lesions is Strongly Sequence and Conformation Dependent

 

Link to publication

48

G. W. Hsu, M. Ober, T. Carell, L. S. Beese

Nature 2004, 431, 217-221.

Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase

 

Link to publication

47

F. Coste, M. Ober, T. Carell, S. Boiteux, C. Zelwer, and B. Castaing

J. Biol. Chem. 2004, 279, 44074-44083.

Structural Basis for the Recognition of the FapydG Lesion (2,6-Diamino-4-hydroxy-5-formamidopyrimidine) by Formamidopyrimidine-DNA Glycosylase

 

Link to publication

46

M. v. Meltzer, M. Marsch, T. Carell and K. Harms

Acta. Cryst. E. 2004, E60, 2515-2516.

(1S,2R,4S,5R)-tert-Butyl 7-oxo-3-oxa-6-azatricyclo[3.2.1.02,4]octane-6-carboxylate

 

Link to publication

45

B. Giese, B. Carl, T Carl, T. Carell, C. Behrens, U. Hennecke, O. Schiemann, E. Feresin

Angew. Chem. Int. Ed. 2004, 43, 1848-1851.

Excess electron transport through DNA: A single electron repairs more than one UV-induced lesion

 

Link to publication

44

C. Behrens, M. Cichon, F. Grolle, U. Hennecke, T. Carell

Top. Curr. Chem. 2004, 236, 187-204.

Excess electron transfer in defined donor-nucleobase and donor-DNA-acceptor systems

 

Link to publication

43

M. Ober, M.Marsch, K. Harms, T. Carell

Act. Cryst. E. 2004, E60, o1191-o1192.

A carbocyclic analogue of a protected a-D-2-deoxyribosylamine

 

Link to publication

42

C. Haas, K. Kräling, M. Cichon, N. Rahe and T. Carell

Angew. Chem. Int. Ed. 2004, 43, 1842-1844.

Excess electron transfer driven DNA repair does not depend on the transfer direction

 

Link to publication

41

S. Breeger, U. Hennecke and T. Carell

J. Am. Chem. Soc. 2004, 126, 1302-1303.

Excess Electron Transfer Based Repair of a cis-syn Thymine Dimer in DNA is only Weakly Sequence Dependent

 

Link to publication

Philipps-Universität Marburg (Germany)

40

M. Ober, U. Linne, J. Gierlich, T. Carell

Angew. Chem. Int. Ed. 2003, 42, 4947-4951.

The two main oxydative DNA lesions 8-oxo-7,8-dihydroguanine and 2,6-diamino-5-formamido-4-hydroxypyrimidine exhibit strongly different pairing characteristics

39

N. Rahe, C. Rinn, T. Carell

Chem. Commun. (Camb.) 2003, 2120-2121.

Development of Donor/Acceptor Modified DNA Hairpins for the Investigation of Charge Hopping Kinetics in DNA

38

A. Mees, C. Behrens, A. Schwögler, M. Ober, T. Carell

Eur. J. Org. Chem. 2003, 2670-2677.

Redoxactive Oligonucleotides: Synthesis and Properties of Flavocoenzyme-DNA

37

C. Behrens, T. Carell

Chem. Commun. (Camb.) 2003, 1632-1633.

Excess Electron Transfer in Flavin-Capped, Thymine Dimer-Containing DNA Hairpins

36

T. Carell, C. Behrens, J. Gierlich

Org. Biomol. Chem. 2003, 1, 2221-2228.

Electron transfer Through DNA and Metal-Containing DNA

35

M. Cichon, C. Haas, F. Grolle, A. Mees, T. Carell

J. Am. Chem. Soc. 2002, 124 13984-13985.

Efficient Interstrand Excess Electron Transfer in PNA:DNA Hybrids

34

L. Kundu, L. Burgdorf, T. Carell

ChemBioChem 2002, 3, 1053-1060.

Thymine Dimer Containing Molecular Beacons for the Investigation of Photolyase Activity in Cell Extracts

33

C. Behrens, M.Ober, T. Carell

Eur. J. Org. Chem. 2002, 3, 3281-3289.

Flavin-Capped DNA Hairpins for Excess Electron Transfer Studies in DNA

32

C. Behrens, L. Burgdorf, A. Schwögler, T. Carell

Angew. Chem. Int. Ed. 2002, 41, 1763-1766.

Shallow distance dependence of excess electron transfer through DNA

31

M. Cichon, S. Arnold, T. Carell

Angew. Chem. Int. Ed. 2002, 41, 767-770.

Repair of the oxetane lesion by (6-4) DNA photolyases requires a reduced and deprotonated flavin

30

L. Burgdorf, T. Carell

Chemistry 2002, 8, 293-301.

Synthesis, stability, and conformation of the Formamidopyrimidine G DNA lesion

29

T. Carell, L. Burgdorf, L. Kundu

Curr. Opin. Chem. Biol. 2001, 5, 491-498.

The Mechanism of Action of Photolyase

28

D. Nikova, B. de Frooth, K. Groener, C. Wyman, A. Eker, T. Carell, J. Greve

Biophys. J. 2000, 78, 1552.

Specific and non-specific interactions in DNA repair processes

27

A. Schwögler, L. Burgdorf, T. Carell

Angew. Chem. Int. Ed. 2000, 39, 3918-3920.

Self-Repairing DNA Based on a Reductive Electron Transfer Through the Base Stack

26

A. Schwögler, T. Carell

Helv. Chim. Acta. 2000, 83, 2452-2463.

Synthesis and Properties of Flavin Nucleosides

25

A. Schwögler, T. Carell

Org. Lett. 2000, 2, 1415-1418.

Towards Catalytically Active Oligonucleotides: Synthesis and Properties of a Flavin Nucleotide and its Incorporation in DNA

24

J. Butenandt, R. Epple, E.-U. Wallenborn, A. Eker, V. Gramlich, T. Carell

Chemistry 2000, 6, 62-72.

DNA-Photolyase Models: A Comparative Cleavage Study With Cyclobutane Uracil- and Thyminedimer Model Compounds

ETH-Zürich (Switzerland)

23

O. Kleiner, J. Butenandt, T. Carell, A. Batschauer

Eur. J. Biochem. 1999, 264, 161-167.

Class II DNA photolyase from Arabidopsis thaliana contains FAD as cofactor

22

J. Butenandt, R. Epple, E.-U. Wallenborn, A. Eker, V. Gramlich, T. Carell

Chemistry 2000, 6, 62-72.

DNA-Photolyase Models: A Comparative Cleavage Study With Cyclobutane Uracil- and Thyminedimer Model Compounds

21

R. Epple, T. Carell

J. Am. Chem. Soc. 1999, 121, 7318-7329.

Efficient Light Dependent DNA-Repair Requires a Large Cofactor Separation

20

J. Butenandt, L. Burgdorf, T. Carell

Angew. Chem. Int. Ed. 1999, 38, 708-711.

"Base Flipping": Photodamaged DNA-RNA Duplexes Are Poor Substrates for Photoreactivating DNA-Repair Enzymes

19

T. Carell, H. Schmid, M. Reinhard

J. Org. Chem. 1998, 63, 8741-8747.

A Convenient Synthesis of a Flavin- and a Deazaflavin-Amino Acid and their Incorporation into Oligopeptides

18

T. Carell, R. Epple

Eur. J. Org. Chem. 1998, 7, 1245-1248.

Repair of UV-light Induced DNA Lesions: A Comparative Study with Model Compounds

17

R. Epple, T. Carell

Angew. Chem. Int. Ed. 1998, 37, 938-941.

Flavin and Deazaflavin Containing Model Compounds Mimic the Energy-Transfer Step in Type II DNA-Photolyases

16

J. Butenandt, A. P. M. Eker, T. Carell

Chemistry 1998, 4, 642-654.

Synthesis, Crystal-Structure and Enzymatic Evaluation of a DNA-Photolesion Isostere

15

T. Carell, R. Epple, V. Gramlich

Helv. Chim. Acta 1997, 80, 2191-2203.

Synthesis and Structure of (Carboxymethyl)-Functionalized Cyclobuta-Fused Uracil Dimers

14

R. Epple, E.-U. Wallenborn, T. Carell

J. Am. Chem. Soc. 1997, 119, 7440-7451.

Investigation of Flavin-Containing DNA-Repair Model Compounds

13

T. Carell, J. Butenandt

Angew. Chem. Int. Ed. 1997, 36, 1461-1464.

Towards Artificial DNA-Repair Enzymes: Incorporation of a Flavin Amino Acid into DNA-Binding Oligopeptides

12

T. Carell, R. Epple, V. Gramlich

Angew. Chem. Int. Ed. 1996, 35, 620-623.

Synthesis of Flavin‐Containing Model Compounds for DNA Photolyase Mediated DNA Repair

10

T. Carell

Chimia 1995, 49, 365-373.

Sunlight-Induced DNA Lesions. Lesion Structure, Mutation Characteristics and Repair

MIT (Cambridge, USA)

9

A. S. Fang, P. Vouros, C. C. Stacey, G. H. Kruppa, F. H. Laukien, E. A. Wintner, T. Carell, J. Rebek

Comb. Chem. & High Throughput Screening 1998, 23-33.

Rapid characterization of combinatorial libraries using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry

8

E. A. Wintner, J. Shipps, T. Carell, J. Rebek, Y. Dunayevskiy, P. Vouros

Proc. Natl. Acad. Sci. USA 1996, 93, 6152-6157.

Application of Capillary Electrophoresis-Electrospray Ionization Mass Spectrometry in the Determination of Molecular Diversity

7

T. Carell, E. A. Wintner, J. Rebek, Jr., Y. Dunayevskiy, P. Vouros

Anal. Chem. 1995, 67, 2906-2915.

Characterization of the Complexity of Small-Molecule Libraries by Electrospray Ionization Mass Spectrometry

5

T. Carell, E. A. Wintner, J. Rebek, Jr.

Angew. Chem. Int. Ed. 1994, 33, 2061-2064.

A Solution-Phase Screening Procedure for the Isolation of Active Compounds from a Library of Molecules

4

T. Carell, E. A. Wintner, A. Bashir-Hashemi, J. Rebek, Jr.

Angew. Chem. Int. Ed. 1994, 33, 2059-2061.

A Novel Procedure for the Synthesis of Libraries Containing Small Organic Molecules

Max-Planck-Institut for Medical Research (Heidelberg, Germany)

4

T. Carell, E. A. Wintner, A. Bashir-Hashemi, J. Rebek, Jr.

Angew. Chem. Int. Ed. 1994, 33, 2059-2061.

A Novel Procedure for the Synthesis of Libraries Containing Small Organic Molecules

3

H. A. Staab, T. Carell

Angew. Chem. Int. Ed. 1994, 33, 1466-1468.

Synthesis and Properties of a Vertically Stacked Porphyrin1-Porphyrin2-Quinone Cyclophane

2

H. A. Staab, T. Carell, A. Döhling

Chem. Ber. 1994, 127, 223-229.

Syntheses and Properties of New Quinone-Bridged Diphenyl- and Tetraphenylporphyrins

1

C. Krieger, M. Dernbach, G. Voit, T. Carell, H. A. Staab

Chem. Ber. 1993, 126, 811-821.

Conformational Mobility and Crystal Structures of Porphyrin-Quinone Cyclophanes

Other publications and activity

17

A. G. Beck-Sickinger, T. Carell, S. Dehnen, W. Leitner, P. R. Schreiner, H. Wennemers

Angew. Chem. Int. Ed. 2020, doi:10.1002/anie.202008469

From Scientists to Scientists—Moving Angewandte into the Future

 

Link to publication

 

16

T. Carell

Angew. Chem. Int. Ed. 2015, doi:10.1002/anie.201509770

DNA Repair.

 

Link to publication

15

E. Parsa, A. Schröder, T. Carell

Naturwissenschaftliche Rundschau 2015, 3, 128-133.

Modifizierte DNA-Basen erweitern das Verständnis der Genregulation

14

Organisation des 8. Nachwuchswissenschaftler Symposiums "Bioorganische Chemie", Heidelberg 20.-22. September 1999

13

T. Carell

Nature (News & Views). 2011, 469, 45-46.

Molecular computing: DNA as a logic operator

12

J. Cadet, T. Carell, L. Cellai, C. Chatgilialoglu, T. Gimisis, M. Miranda, P. O'Neill, J.-L. Ravanat, M. Robert

Chimia, 2008, 62, 742-749.

DNA damage and radical reactions: mechanistic aspects, formation in cells and repair studies

11

T. Carell, P. Cramer, K.-H. Hopfner

Nucleic Acids Symp. Ser. 2008, 15, 103.

The chemistry of transcription through damaged DNA and of translesion synthesis at atomic resolution

10

M. Friedel, M. K. Cichon, T. Carell

CRC Handbook of Photochemistry and Photobiology 2004, 141/1-141/22.

DNA Repair: Photochemistry

9

T. Carell

Nature 2004, 431, 398.

German reform would make little difference

8

P. H. Seeberger, T. Carell

Curr. Opin. Chem. Biol. 2003, 7, 715-716.

Biopolymers

7

Org. Biomol. Chem. 2003, 1, XI.

Profile Thomas Carell

6

T. Carell

Chemie Heute. 2000 ⁄ 2001, 102-105.

Damit unser Erbgut intakt bleibt

5

Verschiedene Beiträge zur Darstellung der Jungen Akademie

4

Organisation des 8. Nachwuchswissenschaftler Symposiums "Bioorganische Chemie", Heidelberg 20.-22. September 1999

3

Chimia, 1997, 12, 952-962.

Conference report about the 36. IUPAC Congress: Frontiers in Chemistry, New Perspectives for the 2000s

1

Angew. Chem. 1996, 108, 990-991try, Book Report: G. Quinkert, E. Egert, C. Griesinger

Aspekte der Organischen Chemie, Struktur, Verlag Helv. Chim. Acta, Basel 1995

Kontakt

Ludwig-Maximilians-Universität München
Fakultät für Chemie und Pharmazie
Arbeitskreis Prof. Thomas Carell
Butenandtstr. 5-13, Building F
81377 Munich, Germany

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